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Kidney Stones and Chronic Kidney Disease

September 5, 2023

Kidney stones are solid mineral formations that develop in the kidneys or the urinary system. They typically arise due to factors such as reduced urine volume or an increase in minerals that contribute to stone formation.

Approximately 1 in 20 individuals will experience kidney stones during their lifetime. Men are three times more likely to develop kidney stones than women, and the condition is more prevalent in Caucasians compared to African Americans.

Kidney stones usually form when there’s insufficient fluid intake (resulting from dehydration due to inadequate hydration or excessive physical activity), an excess of mineral deposits in the urine, and/or lower-than-normal levels of compounds responsible for dissolving these minerals in the urine. These kidney stones can either exit the body through the urinary tract or remain in the kidney, bladder, or urethra.

Symptoms of Kidney Stones

Kidney stones may go unnoticed until they cause discomfort, block the urine flow, or are passed. The most common symptom is intense, intermittent pain in the lower back or side, just below the ribcage. Additional symptoms include:

  • Discolored and foul-smelling urine
  • Nausea and vomiting
  • Fever and chills
  • Painful, burning sensation during urination

If you experience any of these symptoms, consult your healthcare provider promptly. Early management of kidney stones can prevent severe complications, such as chronic kidney disease or, in extreme cases, renal failure necessitating dialysis or kidney transplantation.

Types of Kidney Stones and Their Formation

Kidney stones fall into four main categories:

  1. Calcium Kidney Stones: These are the most common type and are often seen in individuals with elevated vitamin D levels or hyperactive parathyroid glands. People with chronic kidney disease (CKD) are also at higher risk of developing calcium kidney stones.
  2. Struvite Kidney Stones: Typically formed after a urinary tract infection, these stones are more common in women, who tend to experience frequent urinary infections. Struvite stones are often jagged or stag-horn shaped and can grow large, potentially causing kidney damage.
  3. Uric Acid Kidney Stones: Excessive uric acid in the urine is the culprit behind these stones, which are more prevalent in men. High-protein diets can contribute to elevated uric acid levels, and individuals with gout face a greater risk of uric acid stones.
  4. Cystine Kidney Stones: These stones are rare and result from an inherited condition called cystinuria. Typically diagnosed in childhood, individuals with cystinuria require lifelong treatment.

Treatment for Kidney Stones

Determining the type of kidney stone involves analyzing a 24-hour urine collection or examining a passed stone. Many cases do not require surgical intervention, and hydration may facilitate the passage of smaller stones.

For larger or problematic stones, various treatment options are available:

  • Shock Waves: Extracorporeal shock wave lithotripsy (ESWL) involves directing shock waves at the kidney stone. This non-invasive approach doesn’t require surgery or a hospital stay.
  • Nephrolithotomy: This procedure involves a small incision in the back to remove the kidney stone using a nephroscope.
  • Ureteroscopic Stone Removal: A scope is inserted through the bladder to remove stones stuck in the ureter.

Preventing Kidney Stones

Lifestyle adjustments, particularly dietary and exercise habits, can aid in preventing kidney stones. Staying well-hydrated with 2 to 3 quarts of water daily (unless on a fluid-restricted diet) is commonly recommended for individuals with a history of kidney stones. Reducing dietary protein intake can lower the risk of specific stone types.

Additionally, healthcare providers may prescribe medications to regulate the levels of certain minerals in the urine. Some cases involve surgical removal of overactive parathyroid glands, which can prevent the recurrence of calcium kidney stones.

If you’ve had kidney stones, it’s essential to discuss strategies with your doctor to prevent their return and maintain optimal kidney health.

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